Real Madrid welcome Juventus to the Santiago Bernabéu on Wednesday, October 22, 2025, for a crucial UEFA Champions League Matchday 3 clash. The Spanish giants sit second with six points from two matches after back-to-back wins, while Juventus remain winless, occupying 23rd with two points from two draws. Can the Old Lady secure their first UCL campaign victory in Madrid?
Our Real Madrid vs. Juventus predictions guide previews the upcoming midweek game. For more insights about Europe’s elite competition, check out other UEFA Champions League predictions.
Real Madrid vs Juventus Match Information
- Competition: 25/26 UEFA Champions League, League Phase, Round 3
- Venue: Estadio Santiago Bernabeu, Madrid, Spain
- Date: 22 October 2025
- Time: 19:00 GMT on Wednesday
Real Madrid vs Juventus Odds to Win
The official Real Madrid vs Juventus odds are now available from major sportsbooks, with specific details listed below:
- Real Madrid to Win @ 1.45 (4/9)
- Draw @ 4.50 (7/2)
- Juventus to Win @ 6.25 (21/4)
BAR – Juventus: H2H
Real Madrid had won three of their previous five encounters with the Old Ladies, leaving Juventus with two wins during that period.
- Real Madrid 1-0 Juventus (1 July 2025)
- Juventus 3-1 Real Madrid (3 August 2023)
- Real Madrid 2-0 Juventus (31 July 2022)
- Real Madrid 3-1 Juventus (4 August 2018)
- Real Madrid 1-3 Juventus (11 April 2018)
Real Madrid vs Juventus: Interesting Match Stats
- Real Madrid has avoided a goalless result in their last 61 group stage or league phase matches, a run that began after a 0-0 draw with Paris Saint-Germain in October 2015.
- Juventus has only been defeated twice over its past ten European away fixtures, notably settling for a draw in four of its last five such games.
- Real Madrid and Barcelona are tied for the Champions League record with 30 appearances in the competition. Los Blancos also boast a perfect record of qualifying for the knockout stage in all previous 29 campaigns.
Real Madrid Team Analysis
Real Madrid have started their 2025–26 UEFA Champions League campaign in commanding fashion. They earn six points from their opening two fixtures to emerge among the early frontrunners. After a tense 2-1 win over Marseille in September, Los Blancos dismantled Kairat Almaty 5-0 on Matchday 2. Kylian Mbappé netted a hat-trick to seal a comfortable away victory. The 15-time European champions are firmly on course for a top-eight finish in the new league phase.
At home, Madrid has won 12 of their last 13 group or league-stage matches, losing only to AC Milan two years ago. They return to the Bernabéu fresh from a 1-0 La Liga win over Getafe, where Mbappé again delivered the decisive goal. Sitting top of La Liga ahead of El Clásico, Madrid now shifts focus to Juventus.
Real Madrid Line-Up Prediction
Antonio Rudiger, Dean Huijsen, Dani Ceballos, and Dani Carvajal remain sidelined with injuries, although Carvajal’s also suspended. Trent Alexander-Arnold and Ferland Mendy have resumed training but could be reserved for the El Clásico.
Possible starting lineup: Courtois; Valverde, Militao, Asencio, Carreras; Tchouameni, Camavinga; Mastantuono, Guler, Vinicius; Mbappe.
Last 5 Matches: W-W-W-L-W
Juventus Team Analysis
Juventus’ Champions League campaign so far has been defined by frustration and missed opportunities. The Italian giants just two points from their opening two fixtures in the league phase. Having struggled to make an impact in Europe in recent years, Juve finished 20th in last season’s standings before bowing out to PSV Eindhoven in the knockout playoffs. Igor Tudor’s men entered this campaign aiming for a top-eight finish and direct qualification for the last 16, but two chaotic draws have already put them under early pressure.
Matchday one saw a dramatic 4-4 draw with Borussia Dortmund, where Juventus conceded twice late before scoring two stoppage-time goals to salvage a point. A 2-2 stalemate at Villarreal followed, extending their streak to five straight draws in all competitions. With just one win in their last 11 away Champions League games, Juve travel to Madrid desperate to spark their campaign into life.
Juventus Line Up Prediction
Juventus will be without key defender Gleison Bremer for this crucial clash, along with Arkadiusz Milik, Juan Cabal, Fabio Miretti, and summer signing Edon Zhegrova.
Possible starting lineup: Di Gregorio; Gatti, Rugani, Kelly; Kalulu, Locatelli, Thuram, Cambiaso; Conceicao, Yildiz; David.
Last 5 Matches: L-D-D-D-D
Real Madrid vs Juventus Betting Tips & Predictions
Analysis of the latest statistics and team trends has resulted in the selection of the most advantageous betting picks for the Real Madrid vs Juventus match:
- Match Result – Draw @ 4.50 (7/2) — Real Madrid haven’t faced a team with UCL pedigree and have struggled to claim three points in both of their opening fixtures. Similarly, Juventus is not on a stroll either and will seek a better outing at the Bernabeu. However, away victory seem far-fetched considering their recent form. They’ve drawn five of their previous six matches. So we expect them to settle for a draw on Madrid’s turf.
- Total Goals — Over 3.5 @ 2.50 (1/1) – Both sides boast attacking talents, which could lead to a higher score count on Wednesday. Notably, Alonzo’s team has produced an outcome beyond three goals in four of their last five fixtures. This is the case in both Juventus fixtures so far in the tournament. Their head-to-head record also saw a score count of over 3.5 in three of their last five meetings. This trend leans towards another clash with the possibility of an outcome that exceeds three goals.
- Kylian Mbappe To Score @ 1.61 (3/5) – Mbappe has had a prolific start to the new campaign in domestic and international competitions. He’s the leading scorer in the UCL with five goals in just two fixtures. The Frenchman has also reached double figures (10) in nine La Liga starts, including his decisive strike against Getafe last Sunday. We expect him to continue his scoring spree against Juve, who have conceded six goals already in the competition.
Final Thoughts & Recommended Picks
This clash is set between two teams with UCL pedigree, and with much at stake for the visitors, they won’t aim for anything less than a point at the Bernabeu. Check below for our recommended Real Madrid vs Juventus predictions.
✅ Match Result – Draw @ 4.50 (7/2)
✅ Kylian Mbappe To Score @ 1.61 (3/5)
