Tominay and Mkhitaryan posing for Napoli vs Inter predictions
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2025/2026 Napoli vs Inter Predictions & Betting Tips (Italian Serie A)

Tominay and Mkhitaryan posing for Napoli vs Inter predictions
Tominay and Mkhitaryan posing for Napoli vs Inter predictions

Napoli continue their Sudetto title defense this weekend as they host Inter at the Stadio Diego Armando Maradona. The Nerazzurri enter Saturday’s clash on the back of seven consecutive wins across all competitions, while Antonio Conte’s men have suffered back-to-back defeats. Both sides sit level on 15 points, adding extra weight to this encounter. Can Napoli bounce back and reclaim momentum? Our Napoli vs Inter predictions guide offers a full match preview. You can also check out other Serie A predictions to stay informed about the Italian top division.

Napoli vs Inter Match Information

  • Competition: 25/26 Italian Serie A, Round 8
  • Venue: Stadio Diego Armando Maradona, Naples, Italy
  • Date: 25 October 2025
  • Time: 16:00 GMT on Saturday

Napoli vs Inter Odds to Win

English bookmakers have released Napoli vs Inter odds, with the betting lines summarised below:

  • Napoli to Win @ 2.90 (17/9)
  • Draw @ 3.20 (9/4)
  • Inter to Win @ 2.50 (3/2)

NAP – INT: H2H

Inter has claimed two victories in their previous five meetings with Napoli, while they’ve drawn their last three straight encounters.

  • Napoli 1-1 Inter (1 March 2025)
  • Inter 1-1 Napoli (10 November 2024)
  • Inter 1-1 Napoli (17 March 2024)
  • Napoli 0-1 Inter (22 January 2024)
  • Napoli 0-3 Inter (3 December 2023)

Interesting Match Stats

  • Inter have won their last seven fixtures in a row across tournaments.
  • Napoli have lost two of their last three league matches.
  • Their previous three head-to-head meetings ended in a 1-1 draw.

Napoli Team Analysis

After starting their Serie A title defense with four consecutive wins, Napoli’s momentum has stuttered. They’ve lost two of their last three league outings. Since the international break, Antonio Conte’s injury-hit squad has struggled for rhythm. A 1-0 loss to Torino was followed by a disastrous 6-2 Champions League defeat to PSV Eindhoven in midweek.

That result deeply frustrated Conte, whose side has now lost as many league games in their last three as in their previous 31. Still, Napoli remains formidable at home. Gli Azzurri remain unbeaten in 15 Serie A games at the Stadio Diego Armando Maradona. 

Their last home loss was in December 2024, when they won 12 of those and all three home league fixtures this season. Napoli will hope to continue that strong home form when they host Inter on Saturday.

Napoli Line-Up Prediction

Napoli’s attack was already without former Inter striker Romelu Lukaku before Rasmus Hojlund picked up a thigh strain in training. They also remain without Amir Rrahmani and Stanislav Lobotka.

Possible starting lineup: Meret; Di Lorenzo, Beukema, Buongiorno, Spinazzola; Gilmour; Politano, Anguissa, De Bruyne, McTominay; Lucca.

Last 5 Matches: L-L-W-W-L

Inter Team Analysis

Inter head to Naples in outstanding form, having recorded seven consecutive wins across all competitions. Since their September defeat to Juventus, the Nerazzurri have been flawless in Serie A. In Europe this week, they recorded a 4-0 victory over Belgian champions Union Saint-Gilloise in the Champions League.

Domestically, Inter have claimed four straight league wins against Sassuolo, Cagliari, Cremonese, and Roma. In the latter, Ange-Yoan Bonny extended his goal involvement tally to five in two games across both sides of the international break. 

Defensively, the Nerazzurri have kept four clean sheets in their last five Serie A away fixtures. Their only blemish: a 4-3 loss to Juventus. Encouragingly, they have lost just one of their last 12 Saturday meetings with Napoli, winning five and drawing six.

Line Up Prediction

Marcus Thuram could return for Inter, boosting an attack that rested Bonny in midweek. However, Matteo Darmian remains sidelined through injury.

Possible starting lineup: Sommer; Akanji, Acerbi, Bastoni; Dumfries, Barella, Calhanoglu, Mkhitaryan, Dimarco; Bonny, Martinez.

Last 5 Matches: W-W-W-W-W

Napoli vs Inter Betting Tips & Predictions

After analyzing the stats and recent performance, we’ve zeroed in on the most compelling betting angles for the Napoli vs. Inter clash:

  1. Inter To Win @ 2.50 (3/2) — Inter Milan’s dominant form across all competitions and their recent head-to-head record against Napoli make them clear favourites for victory. The Nerazzurri have won seven consecutive matches and remain unbeaten in their last five meetings with Napoli. With the hosts’ defensive frailties exposed in the heavy loss to PSV Eindhoven, Inter appear well-positioned to continue their winning run.
  2. Both Teams To Score — Yes @ 1.80 (4/5) – Both teams boast attacking depth that makes a clean sheet unlikely. Four of their last five meetings have seen both sides find the net. Napoli have conceded in eight consecutive matches and have seen both teams score in five of their last six. Inter have shown similar trends in three of their last five Serie A fixtures, suggesting Saturday’s clash should deliver goals at both ends.
  3. Lautaro Martinez to Score @ 2.87 (13/7) – Lautaro Martinez will be a major threat to Napoli’s defense in the upcoming league clash. Although not yet at his explosive best this season, he remains central to Inter Milan’s attack. The Argentine netted 12 league goals and nine in the Champions League last term and already has three this season. Napoli’s defensive frailties were exposed again on Tuesday, as they conceded six to PSV. Therefore, Martinez looks well-positioned to get on the scoresheet this weekend.

Final Thoughts & Recommended Picks

Inter has superior form and historical dominance in this fixture, and can claim all three points in Naples. Here are our recommended Napoli vs Inter predictions.

✅ Inter To Win @ 2.50 (3/2)

✅Lautaro Martinez to Score @ 2.87 (13/7)

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